{"id":14518,"date":"2018-02-13T03:30:00","date_gmt":"2018-02-13T03:30:00","guid":{"rendered":""},"modified":"2020-09-25T02:42:52","modified_gmt":"2020-09-25T02:42:52","slug":"mitocondria-uzina-energetica-materiei","status":"publish","type":"post","link":"https:\/\/rubyskynews.com\/index.php\/2018\/02\/13\/mitocondria-uzina-energetica-materiei\/","title":{"rendered":"MITOCONDRIA \u2013 Uzina Energetic\u0103 a Materiei Vii"},"content":{"rendered":"
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MITOCONDRIA \u2013 Uzina Energetic\u0103 a Materiei Vii
Mitocondria este o structur\u0103 celular\u0103 situat\u0103 \u00een citoplasma celulelor eucariote (celule cu un nucleu). Mitocondria este responsabil\u0103 cu transformarea nutrimentelor \u00een energie ce permite moleculelor de Adenozin Trifosfat (ATP) s\u0103 umple activit\u0103\u0163ile celulei. Aceast\u0103 func\u0163ie cunoscut\u0103 \u015fi ca respira\u0163ia aerob\u0103, este motivul pentru care mitocondria este numit\u0103 uzina energetic\u0103 a celulei. Mitocondria este un organit celular neobi\u015fniut care con\u0163ine acid dexosiribonucleic (ADN), g\u0103sit \u00een general la nucleul celulei, \u015fi ribozomi. Aceasta mai produce \u015fi proteine care abund\u0103 \u00een citoplasm\u0103. \u00cen mitocondrie, ADN \u2013ul dirijeaz\u0103 ribozomii \u00een a\u015fa fel, pentru ca ace\u015ftia s\u0103 produc\u0103 proteine, care \u00een mare majoritate func\u0163ioneaz\u0103 ca enzime, sau catalizatori biologici, \u00een produc\u0163ia de Adenozin Trifosfat (ATP). Num\u0103rul mitocondriilor \u00eentr-o celul\u0103 difer\u0103 \u00een fun\u0163ie de rolul celulei (func\u0163ia acesteia). Celulele cu particularit\u0103\u0163i \u00een solicitarea de energie, de c\u0103tre organism, cum ar fi celulele mu\u015fchilor, au mai multe mitocondrii ca oricare alt\u0103 celul\u0103.
Structura Mitocondriei Un mitocondrion (\u2018scheletul\u2019 mitocondriei) este de obicei lung \u015fi sub\u0163ire, dar poate fi v\u0103zut la microscopul electronic, sub form\u0103 de fasole sau oval\u0103. M\u0103rimea acesteia este \u00eentre 0,5- 1 microni. Scheletul mitocondriei are o membran\u0103 dubl\u0103 care formeaz\u0103 un sac \u00een interiorul altui sac. Membrana fin\u0103 din exterior stocheaz\u0103 numeroase proteine transportabile, care expediaz\u0103 materialele \u00een interiorul \u015fi \u00een afara mitocondrionului. Regiunea dintre membranele externe \u015fi interne, care este umplut\u0103 cu lichid, este cunoscut\u0103 sub numele de compartimentul extern. Membrana intern\u0103 are numeroase indoituri (cute) care se numesc cristae. Acestea sunt p\u0103r\u0163ile sintezei ATP- ului, \u015fi structura lor pliat\u0103 cre\u015fte aria unde sinteza ATP- ului are loc. Proteinele transportabile, moleculele numite lan\u0163uri de electroni, \u015fi enzimele care sintetizeaz\u0103 ATP- ul se afl\u0103 de-a lungul moleculelor care se afl\u0103 \u00een cristae. Acestea (cristae) \u00eenchid o regiune umplut\u0103 cu lichid cunoscut\u0103 sub numele Matricea, care con\u0163ine un num\u0103r mare de enzime care sunt folosite \u00een procesul de respira\u0163ie aerob\u0103.
Func\u0163ia Mitocondriei Func\u0163ia de baz\u0103 a mitocondriei este s\u0103 creeze energie pentru activitatea celular\u0103 pe l\u00e2ng\u0103 procesul de respira\u0163ie aerob\u0103. \u00cen acest proces, glucoza este sf\u0103r\u00e2mat\u0103 de c\u0103tre celulele din citoplasm\u0103 pentru a forma un acid piruvic, care este transportat \u00een mitocondrion. \u00centr-o serie de reac\u0163ii, \u00een care o parte este numit\u0103 ciclul acidului citric sau ciclul Krebs, acidul piruvic reac\u0163ioneaz\u0103 cu apa pentru a produce dioxid de carbon (CO2) \u015fi zece atomi de hidrogen.Ace\u015fti atomi de hidrogen sunt transporta\u0163i pe o carier\u0103 transportoare special\u0103 de molecule, numite coenzimi, spre cristae, unde acestea sunt donate lan\u0163ului de transport al electronilor.Acest lan\u0163 de electroni separ\u0103 electronul \u015fi protonul \u00een fiecare din cei zece atomi de hidrogen. Cei zece electroni separa\u0163i sunt trimi\u015fi prin lan\u0163ul transportor \u015fi unii, eventual, se combin\u0103 cu oxigenul (O2) \u015fi cu protonii pentru a forma ap\u0103 (H2O).Energia este eliberat\u0103 \u00een timp ce electronii curg din coenzimi de-a lungul lan\u0163ului transportor de elctroni c\u0103tre atomii de oxigen, \u015fi aceast\u0103 energie este blocat\u0103 de c\u0103tre componentele lan\u0163ului transportor. \u00cen timp ce electronii curg de la un component la altul , componentele pompeaz\u0103 protoni \u00een mod aleatoriu de la matrice la compartimentul extern. Protonii nu se pot \u00eentoarce la matrice cu excep\u0163ia unuia cere este punte de leg\u0103tur\u0103 prin enzimea ATP, care este localizat\u0103 \u00een membrana interioar\u0103. Respira\u0163ia aerob\u0103 este un proces care continu\u0103, astfel c\u0103 mitocondria poate produce sute \u015fi mii de molecule de ATP la fiecare minut \u00een fiecare celul\u0103 tipic\u0103. ATP- ul este transportat \u00een citoplasma celulei, unde este folosit \u00een fiecare reac\u0163ie la care particip\u0103. \u00cen timp ce ATP- ul este folosit, acesta este transformat \u00een ADP, care este returnat de c\u0103tre celul\u0103 \u00een mitocondrion \u015fi este folosit pentru a produce mai mult ATP.
Originea Mitocondriei Mitocondria are tr\u0103s\u0103turi semnificative care seam\u0103n\u0103 cu cele ale procariotelor, celule primitive c\u0103rora le lipse\u015fte nucleul. ADN- ul mitocondrial este circular, ca ADN- ul procariotelor, \u015fi ribozomii mitocondriali care sunt similari ribozomilor procariotelor. Mitocondria se divide independent de celul\u0103 prin intermediul fisiunii binare, metod\u0103 a diviziunii celulei tipic\u0103 procariotelor.Procariotele ca tr\u0103s\u0103turile mitocondriei conduc mul\u0163i savan\u0163i s\u0103 sus\u0163in\u0103 ipoteza endosimbiozei. Ipoteza afirm\u0103 c\u0103 acum milioane de ani \u00een urm\u0103, procariotele tr\u0103iau libere fiind capabile de respira\u0163ie aerob\u0103 erau \u00eenghi\u0163ite de altele(mai mari) dar nu \u015fi digerate, acest lucru nefiind posibil din cauz\u0103 c\u0103 acestea erau rezistente enzimelor. Cele dou\u0103 celule au developat o rela\u0163ie simbiotic\u0103 sau cooperativ\u0103 \u00een care nutrimentele erau \u00eenghi\u0163ite pentru a sus\u0163ine respira\u0163ia aerob\u0103, care furniza celulei gazd\u0103 surplusuri de ATP.Celulele \u00eenghi\u0163ite au evoluat \u00een mitocondria de ast\u0103zi, care re\u0163in ADN \u015fi ribozomi caracteristic str\u0103mo\u015filor lor procariotici.<\/p>\n

Cercet\u0103ri Recente Asupra Mitocondriei ADN- ul \u00een mitocondrie este folosit pentru a da de urm\u0103 unor boli genetice , \u015fi pentru a da de urm\u0103 organismelor antice care con\u0163in celule eucariote. La multe specii de animale, mitocondria tinde s\u0103 urmeze o mo\u015ftenire p\u0103rinteasc\u0103. C\u00e2nd o celul\u0103 se divide, mitocondria se replicheaz\u0103 independent de nucleu. Cele dou\u0103 celule fiice formate dup\u0103 diviziunea celulei, fiecare primind jum\u0103tate de mitocondrie c\u00e2t timp citoplasma se divide. C\u00e2nd un ou este fertilizat de o sperm\u0103, sperma mitocondriei este l\u0103sat\u0103 \u00een afara oului. Zigotul fertilizat mo\u015ftene\u015fte doar mitocondria matern\u0103. Aceast\u0103 mo\u015ftenire matern\u0103 creeaz\u0103 un arbore genealogic care nu este afectat de c\u0103tre tipica amestecare a genelor care are loc \u00eentre partea matern\u0103 \u015fi cea patern\u0103.C\u00e2t timp ADN- ul din mitocondrie direc\u0163ioneaz\u0103 sinteza enzimelor pentru respira\u0163ia aerob\u0103, aceasta deasemenea codific\u0103 pentru proteine, lucru important \u00een sistemul nervos, \u015fi cel circulator \u015fi pentru alte func\u0163ii ale corpului. Un num\u0103r de boli genetice, incluz\u00e2nd diabetul, boala inimii, sindromul Alzheimer, Parkinson- ul, \u015fi Neuropatia Ereditar\u0103 Optic\u0103 a lui Leber, o condi\u0163ie a insuficien\u0163ei optice (individul nu mai vede) par\u0163ial\u0103 sau total\u0103, sunt asociate cu muta\u0163ii \u00een ADN- ul mitocondrial. O specialitate medical\u0103 relativ nou\u0103 este Medicina Mitocondrial\u0103, care caut\u0103 s\u0103 \u00een\u0163eleag\u0103 rolul muta\u0163iilor ADN- ului mitocondrial \u00een bolile genetice.O recent\u0103 compara\u0163ie a mostrelor de ADN uman \u015fi mitocondrial sugereaz\u0103 c\u0103 oamenii au derivat dintr-o femeie care a tr\u0103it \u00een Africa acum circa 140000 sau 290000 de ani \u00een urm\u0103. Mostre genetice luate din etniile africane, asiatice, australiene, europene \u015fi din cele din Noua Guinee relev\u0103 un num\u0103r specific de tipuri de ADN mitocondrial. Compara\u0163ia dintre aceste tipuri de ADN au dus savan\u0163ii s\u0103 construiasc\u0103 un arbore genealogic care arat\u0103 c\u00e2nd fiecare grup a evoluat probabil din cel precedent. \u00cen acest arbore, ADN- ul mitocondrial african ocup\u0103 cele mai \u00eentinse \u015fi vechi ramuri, d\u00e2nd via\u0163\u0103 celorlalte grupuri etnice.Probabil c\u0103 \u00een acea vreme existau multe alte femei a a\u015fa numitei Eve mitocondriale, dar liniile lor maternale mo\u015ftenite au murit.Acest lucru se \u00eent\u00e2mpl\u0103 atunci c\u00e2nd o genera\u0163ie dintr-o famile nu poate avea o fiic\u0103.Un alt folos al ADN- ului mitocondrial este \u00een stiin\u0163a legal\u0103 (judiciar\u0103).Cu ajutorul acestuia (ADN mitocondrial) s-au identificat structura schele\u0163ilor familiei \u0162arului Nicolae al II- lea.ADN- ul mitocondrial al unei rude materne a \u0163arului (\u00eenc\u0103 \u00een via\u0163\u0103) se potrivea exact cu r\u0103m\u0103\u015fi\u0163ele so\u0163iei \u0163arului, Alexandra, \u015fi celor trei copii. Dar din cauz\u0103 c\u0103 ADN- ul mitocondrial a fost mo\u015ftenit doar pe linie matern\u0103, ADN- ul mitocondrial al \u0163arului nu s-a potrivit cu al copiilor \u015fi so\u0163iei \u0163arului.<\/p><\/div>\n

<\/div>","protected":false},"excerpt":{"rendered":"

MITOCONDRIA \u2013 Uzina Energetic\u0103 a Materiei ViiMitocondria este o structur\u0103 celular\u0103 situat\u0103 \u00een citoplasma celulelor eucariote (celule cu un nucleu). Mitocondria este responsabil\u0103 cu transformarea nutrimentelor \u00een energie ce permite moleculelor de Adenozin Trifosfat (ATP) s\u0103 umple activit\u0103\u0163ile celulei. Aceast\u0103 func\u0163ie cunoscut\u0103 \u015fi ca respira\u0163ia aerob\u0103, este motivul pentru care mitocondria este numit\u0103 uzina energetic\u0103 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[1],"tags":[],"aioseo_notices":[],"yoast_head":"\nMITOCONDRIA \u2013 Uzina Energetic\u0103 a Materiei Vii - Jobs\/ Internships\/ Scholarships\/<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rubyskynews.com\/index.php\/2018\/02\/13\/mitocondria-uzina-energetica-materiei\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"MITOCONDRIA \u2013 Uzina Energetic\u0103 a Materiei Vii - Jobs\/ Internships\/ Scholarships\/\" \/>\n<meta property=\"og:description\" content=\"MITOCONDRIA \u2013 Uzina Energetic\u0103 a Materiei ViiMitocondria este o structur\u0103 celular\u0103 situat\u0103 \u00een citoplasma celulelor eucariote (celule cu un nucleu). Mitocondria este responsabil\u0103 cu transformarea nutrimentelor \u00een energie ce permite moleculelor de Adenozin Trifosfat (ATP) s\u0103 umple activit\u0103\u0163ile celulei. 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